Cambridge Healthtech Institute’s Third Annual
Bispecific Antibody Therapeutics
PepTalk: The Protein Science Week
January 13-19, 2014
Creating bioactive molecules that are multivalent and multifunctional offers the promise of more effective therapeutics. By binding to at least two molecular targets simultaneously, antibodies are empowered, thereby delivering a highly potent therapeutic, particularly for cancer immunotherapy. This meeting will explore the challenges of engineering multi-specificity to ensure stability and efficacy, and will review the numerous forms of multi-specific antibodies.
Safety issues will be given particular focus, as will PK and immunogenicity. Case studies will be presented that highlight preclinical development, as well as clinical data. Join colleagues from around the world in this discussion of the exciting breakthroughs in engineering antibodies, and see how cancer and other applications are advancing into a true therapeutic revolution.
We invite presentation proposals on the following preliminary topics:
- Case studies
- Cancer
- Antitumor activity
- Tumor specific antigens (TSAs)
- Stability
- Bi- and trispecific antibodies
- Engineering multivalency
- Variable domains
- Binding specificities
- Diabodies/single-chain antibodies
- Fabs
- Quadromas
- Bi-specific T-cell engagers (BiTEs)
- Antibody mimetics
- Antibody-antigen binding kinetics
- Immunogenicity
- Effector functions
- Clinical applications
Please click here to submit a speaking proposal for review.
Deadline for submission: June 7, 2013
All proposals are subject to review by the Scientific Advisory Committee to ensure the overall quality of the conference program. Please note that due to limited speaking slots, preference will be given to abstracts from those within pharmaceutical and biopharmaceutical companies, regulators and those from academic centers. Additionally, as per CHI policy, a select number of vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
For questions about the meeting, contact:
Mary Ruberry
Conference Director
Cambridge Healthtech Institute
Phone: 781-972-5421
Email: mruberry@healthtech.com
For partnering & sponsorship information, please contact:
Companies A-K
Jason Gerardi
Manager, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5452
Fax: 781-972-5470
Email: jgerardi@healthtech.com
Companies L-Z
Carol Dinerstein
Director, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5471
Fax: 781-972-5470
Email: dinerstein@healthtech.com