January 13 - 17, 2014
Renaissance Hotel and Palm Springs Convention Center Palm Springs, California

A Community Dedicated to the
Evolving Field and Future of Biotherapeutics

Conference DVDs

Recorded at PepTalk 2013


SC2 DVD Cover ThumbStrategies for Protein Purification and Overcoming Aggregation 
Together with input from Sarah Bondos from Texas A&M University, Mario Lebendiker of the Wolfson Centre for Applied Structural Biology at The Hebrew University of Jerusalem provides an indepth overview of protein purification with a particular focus on aggregation problems.

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SC7 DVD Cover ThumbAntibody-Drug Conjugates: Engineering for Safety & Success 
This course provides a detailed look into the discovery, characterization, and manufacturing of Antibody-Drug Conjugates, with a particular focus on safety issues. Featured is an in-depth and extensive case study from Genentech about their use of antibody-drug conjugates in a robust bio-oncology program, including a focus on risk mitigation and risk minimization strategies. This talk is followed by a presentation about Sutro Biopharma's Open Cell Free Synthesis (OCFS) technology for screening, selecting and formulating ADCs. Finally, an excellent overview of the infrastructure required to produce these molecules is presented by Lonza. All three presentations are filled with first-hand insights and practical approaches to successfully developing these potent biologics.

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SC9 DVD Cover ThumbIntegrating Human Factors Engineering (HFE) into Drug Delivery: Get It Right the First Time 
In this DVD, we will provide a baseline understanding of the regulatory need, common practices and real world examples of integrating Human Factors Engineering into a drug development activity.

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Recorded at PepTalk 2012


Transient Protein Production DVD CoverTransient Protein Production In Mammalian Cells: A Short Story 
This short course will introduce the fundamental concepts needed to establish transient protein production in mammalian cells. This will allow for the rapid generation of milligram to gram quantities of recombinant proteins for therapeutic, functional, and structural studies.

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Transient Protein Production DVD CoverHow to Obtain Reliable Information from DLS and Multi-Detector SEC Systems for Biophysical Characterization 
Since its market introduction circa 30 years back, dynamic light scattering (DLS) has occupied a position of increasing popularity within the area of protein aggregate detection and characterization, due in large part to the non-invasiveness of the technique, the minimal sample volume & concentration requirements, and the quickness of data collection.

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Harnessing CHO Cells DVDHarnessing CHO Cells: The Work Horses Of Bioproduction 
Chinese hamster ovary (CHO) cells are the predominant cell factory for the production of biotherapeutics. Nevertheless, even with the recently released CHO cell DNA sequence, more research is required to harness their production potential.

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2012 Characterization and Analysis of Particulates DVD CoverCharacterization and Analysis of Visible and Sub-Visible Particulates 
Sub-visible particles present in these biopharmaceutical products are a product quality attribute and a potential patient safety concerns yet to be fully explored. Early and consistent particle detection, quantitation and control throughout the product life cycle of these drugs from development to commercial lot release is critical in mitigating any concerns.

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Recorded at PepTalk 2011


Characterization and Analysis of Particulates DVD CoverCharacterization and Analysis of Particulates 
Sub-visible particles present in these products are a product quality attribute and a potential patient safety concern yet to be fully explored. Early and consistent particle detection, quantitation and control throughout the product life cycle of these drugs from development to commercial lot release is critical in mitigating any concerns. 

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2011 SC2 DVD CoverProtein Crystallization - Delineating Protein Structure
The "Protein Crystallization" DVD provides both an overview of crystallizing proteins as well as an introduction to crystallography.  The particular challenges of crystallizing Membrane Proteins are addressed, and innovations for automating protein crystallization are included.

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Short Course 4 DVD CoverDynamic Light Scattering Theory, Do's & Don'ts, and Data Interpretation
Since its market introduction circa 30 years back, dynamic light scattering (DLS) has occupied a position of increasing popularity within the area of protein aggregate detection and characterization, due in large part to the non-invasiveness of the technique, the minimal sample volume & concentration requirements, and the quickness of data collection.

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2011 SC6 DVD CoverAffecting Effector Functions to Optimize the Efficacy of Therapeutic Antibodies
Modifying antibodies' effector functions offers a promising technology for creating more efficacious therapeutics.  The "Affecting Effector Functions" DVD provides both an excellent overview by Bill Strohl of how effector functions are currently being engineered by leading companies around the world, and also a case study from Chris Reyes illustrating how it's done.

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2011 Keynote DVD CoverHighlights of Biotherapeutics and Higher-Throughput Protein Expression
Pipeline Three explores the pioneering world of protein-based therapeutics, from novel constructs to enhanced in vivo effects. Pipeline Four provides the latest science and developments on topics covering all aspects of protein science, discovery, analysis, characterization, development and expression of these valuable and promising therapeutics.

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PTK Event APP 
New this year!
The PepTalk App will allow attendees to browse the agenda, create custom schedules, navigate the exhibit hall and explore poster presentations.

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      Premier Sponsors: 

EMD Millipore 

 Novozymes (white) 

PerkinElmer NEW 2009 

 Protein Simple  

  

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Training Seminars 

Mon-Tues, January 13-14 

Biologics Formulation and Delivery  

 


Buzz Sessions
BuzZ Sessions are facilitated, small-group discussions. Interactive participation leads to problem-solving solutions and future collaborations around focused topics.
Click here for BuzZ topics