January 13 - 17, 2014
Renaissance Hotel and Palm Springs Convention Center Palm Springs, California

A Community Dedicated to the
Evolving Field and Future of Biotherapeutics
2014 Archived Content

SHORT COURSE 2: ANTIBODY HUMANIZATION VIA ONE HOT HOMOLOGY MODEL (HANDS-ON) WORKSHOP*

 

Sunday, January 12 | 5:00-8:00 pm



Recent advances in antibody homology modeling have led to the creation of different strategies to design, engineer and affinity mature as well as humanize antibodies. In silico modeling not only helps in better antibody design but also saves time from predictions to validation.

The topics to be covered:

  • Create antibody homology model from the primary sequence
  • Humanization strategies based on the antibody homology model
  • Force field energy minimizations
  • Steric clashes within the humanized antibody and rational methods to fix it
  • Affinity maturation of the humanized antibody

 

*All materials, including tutorials/exercises and scripts, will be available for users during and after the workshop. No prior programming experience necessary. Please bring your laptop for the workshop.

Instructor:

Vinodh Kurella, Ph.D., Visiting Research Fellow, C3 Bioinformatics, Harvard Medical Schoolx


Speaker Biography

Vinodh Kurella, Ph.D., Visiting Research Fellow, C3 Bioinformatics, Harvard Medical School



«Back to Short Courses

Japan-Flag Korea-Flag China-Simplified-Flag China-Traditional-Flag 


PTK Event APP 
New this year!
The PepTalk App will allow attendees to browse the agenda, create custom schedules, navigate the exhibit hall and explore poster presentations.

2014 Brochure Cover 

Right Arrow Download the Brochure 

Right Arrow Event at-a Glance 

      Premier Sponsors: 

EMD Millipore 

 Novozymes (white) 

PerkinElmer NEW 2009 

 Protein Simple  

  

Right Arrow View All Sponsors 

Right Arrow View Media Partners 

Add to Outlook Add to Outlook 

Training Seminars 

Mon-Tues, January 13-14 

Biologics Formulation and Delivery  

 


Buzz Sessions
BuzZ Sessions are facilitated, small-group discussions. Interactive participation leads to problem-solving solutions and future collaborations around focused topics.
Click here for BuzZ topics