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2014 Archived Content

SHORT COURSE 9: IN SILICO IMMUNOGENICITY PREDICTIONS (HANDS-ON) WORKSHOP*

 

Tuesday, January 14 | 5:00-8:00 pm



Computational immunogenicity predictions for antibodies as well as pathogens help in the rational design and re-engineering. This facilitates the minimization of anti-drug antibodies (ADA) as well as better vaccine design. The latest in silico tools can shorten the process from design to preclinical validations.

  • Computational prediction for T cell and B cell epitopes from primary sequences
  • Antigen structure prediction via protein homology model
  • Structure or homology model-based vaccine design
  • In silico anti-drug antibodies prediction
  • Structural differences between MHC-I and MHC-II binding

 

*All materials, including tutorials/exercises and scripts, will be available for users during and after the workshop. No prior programming experience necessary. Please bring your laptop for the workshop

Instructor:

Vinodh Kurella, Ph.D., Visiting Research Fellow, C3 Bioinformatics, Harvard Medical School


Speaker Biography

Vinodh Kurella, Ph.D., Visiting Research Fellow, C3 Bioinformatics, Harvard Medical School



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