Cambridge Healthtech Institute’s 4th Annual
Higher-Throughput Protein Purification
January 22-23, 2015
High-throughput processes have transformed the traditional protein-by-protein trial-and-error approach for testing criteria and scaling up. This leading meeting on Higher-Throughput Protein Purification investigates HTP in the quest to develop methods that ensure quality and translate to large scale. Automation, robotics and liquid handlers will be discussed, along with developing small-scale models that shed light on bioproduction. Case studies illustrate how leaders in the field are integrating HTP approaches in order to reduce the time and effort needed to successfully establish parameters and achieve pure protein.
Automated Higher-Throughput Protein Purification Using Enhanced ÄKTA Chromatography Instruments
Kenneth Walker, Ph.D., Scientific Director, Biologics, Amgen, Inc.
Acceleration of Purification Process Development Using High-Throughput Automation
Srinivas Chollangi, Ph.D., Scientist, Bristol-Myers Squibb Co.
Automation of Non-Chromatographic Downstream Processes Gaining on High-Throughput Bioprocess Development
Cornelia Walther, Ph.D., Scientist, Applied Microbiology, University of Natural Resources and Life Sciences Vienna
Building a High-Throughput Protein Purification Platform
Jiansheng Wu, Ph.D., Senior Scientist, Protein Chemistry, Genentech, Inc.
SEC-TID, a Small Molecule Target ID Platform Utilizing a PDB-Guided Small Molecule-Ligandable Protein Library
Antonin Tutter, Ph.D., Scientific Technical Leader I, Novartis Institutes for BioMedical Research, Inc.
Application of Modular Expression Toolboxes in High-Throughput Protein Expression
Ernst Weber, Ph.D., Lab Head, Protein Engineering and Assays, Bayer HealthCare
High-Throughput Glycosylation Analysis and Monitoring
Pauline M. Rudd, Ph.D., Professor, Glycobiology, National Institute for Bioprocessing Research and Training (NIBRT)
Using High-Throughput Techniques to Produce Difficult Targets: Flavivirus NS1, a Case Study
William (Clay) Brown, Ph.D., Associate Research Scientist, Life Sciences Institute, University of Michigan
High-Throughput Purification of Antibodies and Antibody Fragments Enabling Biologic Drug Discovery
Benjamin Kemp, Ph.D., Senior R&D Manager, MedImmune, LLC
A High-Throughput-Enabled Pipeline for Eukaryotic Expression and Purification
Ronald D. Seidel, III, Ph.D., Director, Macromolecular Therapeutic Development, and Associate Director, Albert Einstein Protein Production Facility, Biochemistry, Albert Einstein College of Medicine
High-Throughput Techniques: Developing Small-Scale Models
Michel Eppink, Ph.D., Head, Downstream Processing, Synthon BV
A Scaled-Down Scale-Down Model: HTPD Case Studies
Douglas MacDonald, Senior Scientist, Purification & Conjugation Development, Seattle Genetics