2019 Archived Content

TUESDAY, JANUARY 15 | 5:45 - 8:45 PM
Room: Aqua 313


Sofie Pattijn, CTO, ImmunXpert

All protein drugs generate an immunogenic response. This short course provides a practical, comprehensive overview of immunogenicity – the causes, how to assess, predictive tools and what to do if you observe immunogenicity during preclinical, clinical and post-market approval. Focus will also be given to immunogenicity for immuno-oncology therapies.

Topics to be Discussed Include:

  • Immunology and major mechanisms affecting immunogenicity
  • Immunogenicity of complex biologics and I/O therapies
  • Pre-clinical prediction and assessment
  • Benefits and limitations of early immunogenicity assessment

Instructor Biography:

Pattijn_SofieSofie Pattijn, CTO, ImmunXperts

Sofie Pattijn (CTO and founder, ImmunXperts) has over 20 years of experience in the field of immunogenicity assessment (vaccines and biotherapeutics) and in vitro assay development. She has extensive hands-on lab experience and has managed and coached several In Vitro teams over the last decade. From 2008 till 2013 she was Head of the In Vitro Immunogenicity group at AlgoNomics (Ghent, Belgium) and Lonza Applied Protein Services (Cambridge, UK). Prior to that, she worked at Innogenetics, Belgium for over 15 years.


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