Expression to Production
The Protein Expression pipeline is a three-part series united by a shared focus on making recombinant protein production faster, more informed, and more reliable, from host selection and platform optimization through expression strategies for the most challenging protein targets. Across the symposium and two conference tracks, attendees will explore how smarter platform choices, improved strategies for difficult targets, and AI-driven approaches are collectively expanding what protein expression teams can achieve. The (Re)Discovering Protein Expression Platforms Symposium centers on host selection and platform optimization, covering cell-free systems, informed cell-based host decisions, and computation-guided engineering for improved expression outcomes. The Recombinant Protein Production-Part 1 track focuses on persistently challenging target classes including GPCRs, membrane proteins, intrinsically disordered proteins, and proteins with difficult post-translational modifications. The Recombinant Protein Production-Part 2 track tackles complex therapeutic formats including multispecifics, T cell engagers, cytokines, miniproteins, and difficult biologics, closing with a practical discussion on optimizing protein production workflows for speed, quality, and impact.
January 18
January 19-20
January 20-21
If you are working in the following areas join the PepTalk community:
- Host Selection and Expression Platform Optimization
- Cell-Free Protein Expression Systems
- Cell-Based Expression Systems
- Recombinant Protein Production
- Protein Expression and Purification
- Difficult-to-Express Protein Targets
- GPCRs and Membrane Proteins
- Intrinsically Disordered Proteins
- Post-Translational Modification Strategies
- Complex Therapeutic Protein Formats
- Multispecifics and T Cell Engagers
- Cytokines, Miniproteins, and Novel Biologics
- AI/ML-Enabled Protein Production Workflows
- Computational Protein Engineering
- In-House, Outsourced, and Hybrid Production Models
- Protein Quality, Yield, and Reproducibility
- Therapeutic Discovery and Development