Developability & Characterization
Developability connects molecular design to clinical and commercial reality. This stream is directed at the experimental and computational scientists who identify, predict, and resolve the biophysical and manufacturing liabilities that determine whether a candidate advances. The pre-conference training seminar and two conference tracks—Analytical Intelligence and Biophysical Methods and Models—cover the wet- and dry-lab tools used to characterize mAbs, bispecifics, ADCs, and emerging modalities including viral vectors and lipid nanoparticles. Topics range from early computational triage through formulation support, IND-enabling studies, and CMC documentation, with direct attention to how AI/ML tools, automation, and higher-order structure methods are changing what is measurable and regulatorily defensible.
January 19-20
January 20-21
If you are working in the following areas join the PepTalk community:
- Aggregation and Colloidal Stability
- Analytical Method Development
- ADC Characterization
- Biophysical Characterization
- Charge Variant and PTM Analysis
- Computational Developability Prediction
- Critical Quality Attributes (CQAs)
- Developability Assessment
- Forced Degradation and Stability
- Formulation Development
- Higher-Order Structure (HOS)
- Immunogenicity Risk Assessment
- Manufacturability and Process Compatibility
- Multispecific and Novel Format Characterization
- Native Mass Spectrometry
- Regulatory Science and CMC Strategy
- Structural Biology (Cryo-EM, NMR, SAXS/SANS)
- Viscosity and Concentration-Dependent Behavior
- Viral Vectors and LNP Characterization