Cambridge Healthtech Institute’s Inaugural

Safety and Efficacy of Bispecific Antibodies, ADCs and Combination Therapy

January 19-20, 2023


The Inaugural Safety and Efficacy of Bispecific Antibodies, ADCs and Combination Therapy at the PepTalk Summit will review clinical successes and milestones of emerging constructs and novel formats for these important assets in the drug development arsenal. The safety and efficacy of bispecifics and ADCs will be examined for molecules in development, and strategies and trends will be shared that address and mitigate toxicity issues. The selection of targets and cancer killing immune effector cells and payload determine many of the safety parameters and will be given full consideration. Join us to explore this critical area of biologics as we set out to chart a course for ensuring the safety of these novel formats.     


Coverage will include, but is not limited to:


  • Impact of target selection on safety of bispecific antibodies
  • Lessons learned from the clinic on bispecifics and ADCs
  • Deciding on the right combination therapy and bispecific construct
  • Choosing the right payload and linker for ADCs
  • Selecting the best pairing of cancer killing immune cell effector function with tumor target
  • Accelerating clinical translation while ensuring safety and efficacy
  • Taking steps to make clinical studies more predictive
  • Designing target-centric ADCs for autoimmune and infectious diseases
  • Mitigation of toxicities to improve efficacy
  • Strategies to enhance the effectiveness of the combination of ADCs with immunotherapy  


The deadline for priority consideration is July 1, 2022.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Christina Lingham

Executive Director, Conferences and Fellow

Cambridge Healthtech Institute

Phone: +1 781-972-5464



For sponsorship information, please contact:


Companies A-K

Jason Gerardi

Sr. Manager, Business Development

Cambridge Healthtech Institute

Phone: +1 781-972-5452



Companies L-Z

Ashley Parsons

Manager, Business Development

Cambridge Healthtech Institute

Phone: +1 781-972-1340