Cambridge Healthtech Institute’s 27th Annual

Recombinant Protein Production – Part 1

January 20-21, 2026

 

Cambridge Healthtech Institute’s 27th Annual Recombinant Protein Production – Part 1: Targets concentrates on how to drive higher-yield, higher-quality output once a host system is chosen. Presenters will outline the latest vector architectures, codon-optimization rules, promoter timing tricks, and temperature or media shifts that push CHO, HEK, insect, bacterial, and cell-free cultures to deliver difficult-to-express proteins, GPCRs, IDPs, and large complexes at higher titers. New assays for real-time quantification of intracellular product and host-cell health will reveal where production stalls and how to correct metabolic bottlenecks before they erode yield. A spotlight on host-cell selection will set the stage, but the core agenda dives into practical, bench-tested tactics for squeezing more functional protein out of every flask and bioreactor. Share your best data in a podium, poster, or sponsor slot and help the field raise the ceiling on producing recombinant protein targets.

 

Coverage will include, but is not limited to:

 

Membrane Proteins and Difficult-to-Express Proteins

  • Cell-free systems in the context of DTEPs and membrane proteins(CHO, E. coli, HEK, etc.)
  • Comparative analysis of different expression systems
  • Target protein production
    • GCPRs
    • Protein scaffolds
    • Intrinsically disordered proteins (IDPs)
    • Large proteins
    • Protein complexes
    • Multi-functional proteins
    • Reagent production
    • Targets with difficult PTMs
    • Calcium and sodium channels
    • Signal transduction complexes
    • Peptides

Assay Development

  • Quantifying how much of the protein is being produced inside the cell
  • Host cell viability and metabolic assays

Unlocking High-Titer Biologics: Strategic Decisions in Cell Culture

  • Vector construct design
    • codon optimization
  • Media temperature selection and optimizing culture conditions
    • cold snap production of CHOs
    • detecting media contamination
  • Tailoring promoters to control protein production timing and level

 

The deadline for priority consideration is June 27, 2025.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

Opportunities for Participation:

 


For more details on the conference, please contact:

Nikki Cerniuk

Conference Producer

Cambridge Healthtech Institute

Phone: 781-972-5400

Email: ncerniuk@healthtech.com

 

For sponsorship information, please contact:

 

Companies A-K

Jason Gerardi

Sr. Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-5452

Email: jgerardi@healthtech.com

 

Companies L-Z

Ashley Parsons

Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-1340

Email: ashleyparsons@healthtech.com