Cambridge Healthtech Institute’s 26th Annual
Recombinant Protein Production – Part 1
January 14-15, 2025
Cambridge Healthtech Institute's 26th Annual Recombinant Protein Production – Part 1 track dives deep into the challenges and solutions for producing a wide range of recombinant protein targets. From discovery research to clinical applications, the demand for high-quality protein biomolecules is ever-growing. This conference addresses the hurdles associated with obtaining these valuable molecules and explores innovative strategies to achieve stable and functional recombinant proteins in a cost and time-effective manner. Join us for the 26th Annual Recombinant Protein Production - Part 1 conference to discover cutting-edge solutions and tools for optimizing the expression of membrane proteins, difficult to express proteins, and more!
Coverage will include, but is not limited to:
Optimizing Recombinant Protein Expression for Discovery
- Tailoring promoters to control protein production timing and level
- Time and cost-conscious production
- Library design and analysis of large data sets for host cell, vector, and construct selection
- Codon optimization
- Avoiding aggregation
- Inclusion body formation
- Optimizing media and culture conditions
- Improving protein folding, solubility, stability, and function
- Overcoming misfolding
Membrane Proteins
- Improving the Stability and Expression of Membrane Proteins
- peripheral membrane proteins
- integral membrane proteins
- transmembrane proteins
- lipid anchored proteins
- Glycosylation modification
- Matching your host to your protein of choice
- CHO
- Yeast
- Baculovirus-Insect
- Bacterial
- Mammalian
- Applications of high-throughput cell free systems: microfluidic devices and lysate optimization
Other Difficult to Express Targets
- Improving stability and expression of proteins
- AAVs,
- VLPs
- Spike proteins
- Kinases
- Intrinsically disordered proteins (IDPs)
- Matching your host to your protein of choice
- Modulating glycosylation
- Applications of high-throughput cell free systems: microfluidic devices and lysate optimization
Novel Targets and Next-Gen Technologies in Recombinant Protein Production
- Alpha fold applications
- Post translational modifications (PTMs)
- Machine learning and construct design
- Biophysical techniques for protein characterization (Cyro-EM) (MS)
- Integrating automation
The deadline for priority consideration is June 28, 2024.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: