Cambridge Healthtech Institute’s 27th Annual
Recombinant Protein Production – Part 1
January 20-21, 2026
Cambridge Healthtech Institute’s 27th Annual Recombinant Protein Production – Part 1: Targets concentrates on how to drive higher-yield, higher-quality output once a host system is chosen. Presenters will outline the latest vector architectures, codon-optimization rules, promoter timing tricks, and temperature or media shifts that push CHO, HEK, insect, bacterial, and cell-free cultures to deliver difficult-to-express proteins, GPCRs, IDPs, and large complexes at higher titers. New assays for real-time quantification of intracellular product and host-cell health will reveal where production stalls and how to correct metabolic bottlenecks before they erode yield. A spotlight on host-cell selection will set the stage, but the core agenda dives into practical, bench-tested tactics for squeezing more functional protein out of every flask and bioreactor. Share your best data in a podium, poster, or sponsor slot and help the field raise the ceiling on producing recombinant protein targets.
Coverage will include, but is not limited to:
Membrane Proteins and Difficult-to-Express Proteins
- Cell-free systems in the context of DTEPs and membrane proteins(CHO, E. coli, HEK, etc.)
- Comparative analysis of different expression systems
- Target protein production
- GCPRs
- Protein scaffolds
- Intrinsically disordered proteins (IDPs)
- Large proteins
- Protein complexes
- Multi-functional proteins
- Reagent production
- Targets with difficult PTMs
- Calcium and sodium channels
- Signal transduction complexes
- Peptides
Assay Development
- Quantifying how much of the protein is being produced inside the cell
- Host cell viability and metabolic assays
Unlocking High-Titer Biologics: Strategic Decisions in Cell Culture
- Vector construct design
- Media temperature selection and optimizing culture conditions
- cold snap production of CHOs
- detecting media contamination
- Tailoring promoters to control protein production timing and level
The deadline for priority consideration is June 27, 2025.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: