Cambridge Healthtech Institute’s 12th Annual

Protein Aggregation and Emerging Analytical Tools

January 20-21, 2021


The popular 12th Annual Protein Aggregation and Emerging Analytical Tools conference covers latest trends, challenges, and solutions in understanding characterization and mitigation of problems generated by protein aggregation in biopharmaceuticals. This conference will feature in-depth case studies, new and unpublished data and interactive discussions on immunogenicity of aggregates, mechanisms of aggregation, new tools for detection, and quantitation of aggregates, and how the data is used in regulatory filings. It will also discuss mechanistic understanding of protein aggregation and present case studies on prevention of particle formation by engineering and formulation approaches, high-concentration protein formulations, aggregation in ADCs, bipecifics, impact of aggregation on production, aggregates as a factor for immunogenicity, and approaches for improvement of biophysical properties of protein solutions.


Coverage will include, but is not limited to:

  • Aggregation and Immunogenicity in protein therapeutics
  • Prediction of aggregates by using computational tools and in silico modeling
  • Rapid and high-throughput tools for prediction and measurement of aggregation, viscosity, and solubility
  • Formulation and process solutions for high-concentration protein formulations
  • New and novel ways to detect aggregates in low- and high-concentration protein formulations
  • Mechanistic understanding and prediction of protein aggregation
  • Preventive and analytical approaches for reduction and removal of aggregates
  • Design of aggregation-resistant biotherapeutics: Ligand interactions that promote protein stability and prevent aggregation
  • Formulation, process, and manufacturing strategies to prevent and overcome aggregation challenges in early- and late-stage development
  • Platform technologies
  • New analytical tools: Development, qualification, and implementation analytical tools for studying protein structure, and dynamics as related to aggregation


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is July 24, 2020.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


If you are selected as a speaker for this virtual event, we request that you pre-record your presentation and be available during the “live” portion January 20-21 for interactive Q&A and panel discussions.  


For more details on the conference, please contact:

Nandini Kashyap, MPharm

Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-972-5406



For partnering and sponsorship information, please contact:

Companies A-K

Jason Gerardi

Senior Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-972-5452



Companies L-Z

Ashley Parsons

Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-1340