Cambridge Healthtech Institute’s 12th Annual
Biotherapeutics Aggregation and Preformulation Strategies
Stability Through Strategy
January 21-22, 2026
This conference highlights the latest advancements and challenges in biotherapeutic aggregation and preformulation strategies. Biotherapeutics aggregation remains one of the most critical issues affecting the safety, efficacy, and stability of therapeutic proteins. Effective preformulation strategies are essential to mitigate these risks and to ensure successful drug development. This conference will feature the latest developments in preformulation strategies including early development screening, analysis, and predictive modeling. Formulation challenges for novel modalities and high concentration biologics are featured with modalities such as Bispecifics, ADCs, fusion proteins, gene therapy products, and peptides.
Over the course of the conference, attendees will engage in in-depth discussions on the molecular mechanisms of biotherapeutic aggregation, analytical techniques for detection and characterization, and innovative formulation approaches to enhance stability.
Coverage will include, but is not limited to:
- Mechanisms and pathways of protein aggregation
- Integration of AI for aggregation risk analysis and decision-making
- Preformulation assessment and design strategies
- Early developability screening for thermal stability, viscosity and solubility
- Charge variant and chemical degradation analysis
- Predictive modeling and computational approaches
- Formulation challenges for novel modalities and high concentration biologics
- Bispecifics, VHHs, ADCs and fusion proteins
- RNA and gene therapy products
- Peptides and miniproteins
The deadline for priority consideration is July 18, 2025.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: