Cambridge Healthtech Institute Training Seminars offer real-life case studies, problems encountered and solutions applied, along with extensive coverage of the academic theory and background. Each Training Seminar offers a mix of formal lecture and interactive
discussions and activities to maximize the learning experience. These Training Seminars are led by experienced instructors who will focus on content applicable to your current research and provide important guidance for those new to their fields.
TUESDAY, JANUARY 21 - WEDNESDAY, JANUARY 22
TS8B: Next-Generation Approaches to Antibody Screening and Discovery
Aqua 303
DAY 1: TUESDAY
2:00 - 5:30 pm Seminar Sessions
DAY 2: WEDNESDAY
8:15 am - 6:05 pm Seminar Sessions
12:15 - 1:15 pm Lunch Provided
6:05 - 7:00 pm Networking Reception in the Exhibit Hall with Poster Viewing
Exhibit Hall Refreshment Breaks also provided.
Instructor:
David Bramhill, PhD, Founder, Bramhill Biological Consulting, LLC
Over the space of a few years, a series of technologies have improved greatly in both capability and affordability, and these have been adapted to enhance the discovery and development of antibodies and other immunotherapies. Among these technologies,
DNA sequencing and data analysis, DNA synthesis, single-cell isolation, and genome engineering using CRISPR/Cas combine to give significant advances in how we can engineer antibodies and cell lines. This training seminar will evaluate these new developments
and their applications in antibody and immunotherapy discovery and development.
Topics to Be Discussed:
- Next-Generation Sequencing of DNA – new capabilities, torrents, and pores
- DNA sequencing applied to single cells and entire immune responses
- Data analysis of whole population responses to immunogen/vaccine
- Cell sorting and other direct isolation-selection of B cells
- Protein-level antibody sequencing capabilities
- Application of new insights to humanization and engineering of IgG
- CRISPR/Cas applied to engineer libraries and cell lines
Instructor:
David Bramhill, PhD, Founder, Bramhill Biological Consulting, LLC
Dr. Bramhill has over 20 years’ experience in biologics, both in large biopharma and startup biotech companies. He has experience in isolating and improving antibodies using phage display and is an inventor on library design techniques for small
scaffolds. He also has experience in diverse expression systems for producing antibodies, antibody fragments and different scaffolds. He has taught numerous technical courses for over 15 years at international conferences.
WHAT IS A TRAINING SEMINAR?
Each CHI Training Seminar offers 1.5 days of instruction, refreshment breaks, exhibit hall functions, and lunch for all registered attendees on the full day of the class. Each person registered for the Training Seminar
will be provided with a hard copy handbook for the Training Seminar in which they are registered. A limited number of additional handbooks may be available for other delegates. CHI encourages track hopping between conference programs,
and we ask that Training Seminars not be disturbed once they have begun. We ask that attendees commit to attending the entire 1.5-day training, and not engage in track hopping once the class has started.
