Cambridge Healthtech Institute’s

Vectors for Targeted Delivery

January 13, 2025


Join us for Cambridge Healthtech Institute's Vectors for Targeted Delivery symposium where we discuss ways to engineer safe and effective vectors, optimize capsids, and perfect payloads. Here we discuss ways to optimize a variety of viral and non-viral vectors through increasing titers, improving tissue specificity, mitigating immunogenicity and cytotoxicity, improving transgene efficiency, implementing machine learning, scaling-up manufacturing, navigating regulatory requirements, and more! Discover groundbreaking advancements with tools and techniques that are furthering mRNA delivery, cell therapy, and gene therapy through the transformative capabilities of vectors.


Coverage will include, but is not limited to: 


Engineering Safe and Effective Vectors

  • Effective engineering of viral vectors:
    • Adeno-associated vectors (AAVs)
    • Adenoviral vectors (Avs)
    • Lentiviral vectors (LVs)
    • Retroviral Vectors
  • Effective engineering of non-viral vectors
    • Lipid nanoparticles (LNPs)
    • Polymer-based vectors
    • Virus-like particles (VLPs)
    • Liposomes
    • Exosomes
    • Gold nanoparticles
  • Applications to mRNA, cell therapy, and gene therapy
  • Increasing infectious titers and improving transgene efficiency
  • Managing systematic toxicity and insertional mutagenesis
  • Improving tissue specificity
  • AI-powered discovery and design of vectors
  • Capsid optimization:
    • Improving capsid permeability
    • Customizing capsid fill-rate
    • Bioconjugation of capsids
    • Managing immunogenicity


From Perfecting the Payload to Targeted Delivery

  • Optimizing encapsulation efficacy and capacity
  • Preserving cargo activity
  • Cassette design for ideal safety and expression profiles
  • Controllable transgene expression
  • Strategies for cellular uptake and endosomal escape
  • Novel vectors for improved delivery


Successful Scale-Up

  • Effective vector manufacturing and scale-up
  • Navigating regulatory requirements
  • Improving yield
  • Quality control


The deadline for priority consideration is June 28, 2024.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:


For more details on the conference, please contact:

Nikki Cerniuk

Conference Producer

Cambridge Healthtech Institute

Phone: +1 781-972-1350



For sponsorship information, please contact:


Companies A-K

Jason Gerardi

Sr. Manager, Business Development

Cambridge Healthtech Institute

Phone: +1 781-972-5452



Companies L-Z

Ashley Parsons

Manager, Business Development

Cambridge Healthtech Institute

Phone: +1 781-972-1340