PLENARY KEYNOTE PANEL
Wednesday, January 22 | 1:45 - 3:05 pm
The PepTalk Plenary Keynote Panel convenes a group of leading scientists working across novel therapeutic modalities and R&D technologies to explore the many challenges associated with discovering, developing, and advancing today’s novel
            biotherapeutics. The Panel, via a highly interactive format, encourages discussion among both the panelists and the audience members. Please come prepared with your questions and ideas for this spirited discussion.
 
- Advances and challenges in expression and production for novel modalities
- Implementing next-generation informatics: data collection, standardization, analysis, ML/AI, and considerations for IP landscape and protection
- Implementing R&D and production capacity for gene and cell therapies – where are we heading?
- Modality-specific challenges: multi-specifics for cancer, improving the ADC therapeutic window, improved safety and pharmacology, novel delivery/targeting
- Preclinical and clinical development of drug combinations with focus in IO: How do we select the right combination dose so we can accelerate clinical development?
Moderator:
 Mohammad Tabrizi, PhD, Senior Director, Pharmacology, Ascendis Pharma A/S
Mohammad Tabrizi, PhD, Senior Director, Pharmacology, Ascendis Pharma A/S
Panelists:
 Edward Kraft, PhD, Senior Scientific Manager, Biomolecular Resources, Genentech
Edward Kraft, PhD, Senior Scientific Manager, Biomolecular Resources, Genentech
 Ilya Shestopalov, PhD, Associate Director, Cell Analytics, bluebird bio
Ilya Shestopalov, PhD, Associate Director, Cell Analytics, bluebird bio
 David E. Szymkowski, PhD, Vice President, Cell Biology, Xencor, Inc.
David E. Szymkowski, PhD, Vice President, Cell Biology, Xencor, Inc.
 Alayna George Thompson, PhD, Senior Scientist I, Drug Discovery Science & Technology, AbbVie
Alayna George Thompson, PhD, Senior Scientist I, Drug Discovery Science & Technology, AbbVie
Additional Conference Keynote Speakers
 Paolo Arosio, PhD, Professor, Biochemical Engineering, Department of Chemistry and Applied Biosciences, ETH Zurich
Paolo Arosio, PhD, Professor, Biochemical Engineering, Department of Chemistry and Applied Biosciences, ETH Zurich
 Phillip Berman, PhD, Distinguished Research Professor, Biomolecular Engineering, University of California, Santa Cruz
Phillip Berman, PhD, Distinguished Research Professor, Biomolecular Engineering, University of California, Santa Cruz
 Murali Bilikallahalli, PhD, Vice President and Head of Technical Operations, Acceleron Pharma
Murali Bilikallahalli, PhD, Vice President and Head of Technical Operations, Acceleron Pharma
 Bryan Briney, PhD, Assistant Professor, Immunology and Microbiology, The Scripps Research Institute
Bryan Briney, PhD, Assistant Professor, Immunology and Microbiology, The Scripps Research Institute
 Partha S. Chowdhury, Senior Director, Biologics Research, Sanofi Genzyme
Partha S. Chowdhury, Senior Director, Biologics Research, Sanofi Genzyme
 Rakesh Dixit, PhD, DABT, President & CEO, Bionavigen, LLC
Rakesh Dixit, PhD, DABT, President & CEO, Bionavigen, LLC
 Aris N. Economides, PhD, Vice President, Research, Regeneron Pharmaceuticals, Inc.
Aris N. Economides, PhD, Vice President, Research, Regeneron Pharmaceuticals, Inc.
 Guangping Gao, PhD, Co-Director, Li Weibo Institute for Rare Diseases Research; Director, Horae Gene Therapy Center
    and Viral Vector Core; Professor, Microbiology and Physiological Systems, University of Massachusetts Medical School
Guangping Gao, PhD, Co-Director, Li Weibo Institute for Rare Diseases Research; Director, Horae Gene Therapy Center
    and Viral Vector Core; Professor, Microbiology and Physiological Systems, University of Massachusetts Medical School
 Mo Heidaran, PhD, Vice President, Technical, PAREXEL Consulting, PAREXEL International
Mo Heidaran, PhD, Vice President, Technical, PAREXEL Consulting, PAREXEL International
 Alois Jungbauer, PhD, Professor and Head, Institute of Bioprocess Science and Engineering, Biotechnology, University
    of Natural Resources and Life Sciences (BOKU)
Alois Jungbauer, PhD, Professor and Head, Institute of Bioprocess Science and Engineering, Biotechnology, University
    of Natural Resources and Life Sciences (BOKU)
 John K. Kawooya, PhD, Director, Biologics Optimization, Discovery Research, Amgen, Inc.
John K. Kawooya, PhD, Director, Biologics Optimization, Discovery Research, Amgen, Inc.
 Josh LaBaer, MD, PhD, Executive Director, Biodesign Institute, Arizona State University
Josh LaBaer, MD, PhD, Executive Director, Biodesign Institute, Arizona State University
 Muthiah (Mano) Manoharan, PhD, Senior Vice President, Drug Discovery, Alnylam Pharmaceuticals, Inc.
Muthiah (Mano) Manoharan, PhD, Senior Vice President, Drug Discovery, Alnylam Pharmaceuticals, Inc.
 Shahram Salek-Ardakani, PhD, Senior Director, Cancer Immunology Discovery, Pfizer
Shahram Salek-Ardakani, PhD, Senior Director, Cancer Immunology Discovery, Pfizer
 Peter Schurtenberger, PhD, Professor, Department of Chemistry, Lund University
Peter Schurtenberger, PhD, Professor, Department of Chemistry, Lund University
 Peter M. Tessier, PhD, Professor, Pharmaceutical Sciences, Chemical Engineering and Biomedical Engineering, University
    of Michigan
Peter M. Tessier, PhD, Professor, Pharmaceutical Sciences, Chemical Engineering and Biomedical Engineering, University
    of Michigan
 Elizabeth M. Topp, PhD, Dane O. Kildsig Chair and Department Head, Department of Industrial and Physical Pharmacy,
    Purdue University
Elizabeth M. Topp, PhD, Dane O. Kildsig Chair and Department Head, Department of Industrial and Physical Pharmacy,
    Purdue University
 Cenk Undey, PhD, Executive Director, Process Development, Amgen
Cenk Undey, PhD, Executive Director, Process Development, Amgen
 Renaud Vincentelli, PhD, Head, High-Throughput Protein Production, Structural Biology Core, Architecture et Fonction
    des Macromolécules Biologiques (AFMB), UMR, CNRS – Aix-Marseille University
Renaud Vincentelli, PhD, Head, High-Throughput Protein Production, Structural Biology Core, Architecture et Fonction
    des Macromolécules Biologiques (AFMB), UMR, CNRS – Aix-Marseille University
 Gerhard Winter, PhD, Professor, Chair, Pharmaceutical Technology and Biopharmaceutics, LMU Munchen
Gerhard Winter, PhD, Professor, Chair, Pharmaceutical Technology and Biopharmaceutics, LMU Munchen